The rare daily word game sweeping the globe. Find what's hidden in plain sight.

NUCLEASE

8 letters

Definition of NUCLEASE

noun

Any of several enzymes capable of cleaving the phosphodiester bonds between the nucleotide subunits of nucleic acids.

Wiktionary · CC BY-SA

Where it comes from

From nucleo- + -ase.

Etymology via Wiktionary (CC BY-SA).

Word DNA

How it is built

nouncompound-asenucleo-

Same root, NUCLEASE · 1 relative in the game

The Word DNA of OUTLIER →

Rarity score
Withheld
Revealed only in play
Tier
Withheld
Find it yourself

OUTLIER scores every word on how unusual it is, and that number is not published. Working it out at the board is the game.

NUCLEASE in OUTLIER

Players have found it on 10 boards so far.

Day 1Day 146
Its 10 boards, across 146 finished boards · taller bars are busier boards
10
Boards found on
84
First board
138
Latest board
16
Longest gap, days

It first turned up on Day 84, 12 August 2026. The most recent board was Day 138, 5 October 2026. Nobody has seen it on a board for 8 days.

First ever to find it

princeoffails

on Day 101, 29 August 2026 - before anyone else in Outlier's history. See the Pioneers

Built from these letters

NUCLEASE
8
Letters
4
Vowels
4
Consonants
7
Different letters
2
Longest consonant run
2
Longest vowel run

NUCLEASE starts with N and ends with E. Sorted, its letters read ACEELNSU - the shape to hunt for when the grid is scrambled. E appears more than once.

Words that start NUCLEA

Its neighbours in the OUTLIER dictionary - shortest first.

Could you have found NUCLEASE?

OUTLIER is a daily word game. One grid, the same grid for everybody, and the words nobody else spots are the ones that pay. This word was on Day 84 - and most players walked straight past it.

Play today's OUTLIER