The rare daily word game sweeping the globe. Find what's hidden in plain sight.

LYSINE

/ˈlaɪsiːn/6 letters

Definition of LYSINE

noun

An amino acid, C6H14N2O2, in L- or D-forms. The L-form of such a molecule, as it occurs in living organisms; in humans it is an essential amino acid.

Wiktionary · CC BY-SA

Where it comes from

From lysis + -ine, in reference to its tendency to participate in catalysis.

Etymology via Wiktionary (CC BY-SA).

Rarity score
Withheld
Revealed only in play
Tier
Withheld
Find it yourself

OUTLIER scores every word on how unusual it is, and that number is not published. Working it out at the board is the game.

LYSINE in OUTLIER

Players have found it on 30 boards so far. 42 players have found it across Outlier's history.

Day 1Day 102
Its 30 boards, across 102 finished boards · taller bars are busier boards
30
Boards found on
11
First board
101
Latest board
15
Longest gap, days

It first turned up on Day 11, 31 May 2026. The most recent board was Day 101, 29 August 2026. Nobody has seen it on a board for 1 day.

First found by a player on Day 11, 31 May 2026.

Built from these letters

LYSINE
6
Letters
2
Vowels
4
Consonants
6
Different letters
3
Longest consonant run
1
Longest vowel run

LYSINE starts with L and ends with E. Sorted, its letters read EILNSY - the shape to hunt for when the grid is scrambled. No letter is used twice, which makes it an isogram.

Same letters, different word

One other word uses exactly these letters. Worth knowing at the board: an anagram fits a grid the same way.

Words that start LYSINE

Its neighbours in the OUTLIER dictionary - shortest first.

LYSINES

Could you have found LYSINE?

OUTLIER is a daily word game. One grid, the same grid for everybody, and the words nobody else spots are the ones that pay. This word was on Day 11 - and most players walked straight past it.

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The OUTLIER card for LYSINEDownload image