The rare daily word game sweeping the globe. Find what's hidden in plain sight.
ISOENZYME
Definition of ISOENZYME
noun
Any of a group of enzymes that catalyze the same reaction but have structures that are (minorly or substantially) different and have physical, biochemical, and immunological properties that are (minorly or substantially) different.
Wiktionary · CC BY-SA
Where it comes from
From iso- + enzyme.
Etymology via Wiktionary (CC BY-SA).
OUTLIER scores every word on how unusual it is, and that number is not published. Working it out at the board is the game.
ISOENZYME in OUTLIER
Players have found it on 1 board so far.
It first turned up on Day 107, 4 September 2026. Nobody has seen it on a board for 4 days.
First ever to find it
on Day 107, 4 September 2026 - before anyone else in Outlier's history. See the Pioneers
Built from these letters
ISOENZYME starts with I and ends with E. Sorted, its letters read EEIMNOSYZ - the shape to hunt for when the grid is scrambled. E appears more than once. It uses Z - among the least common letters in written English.
Words that start ISOENZ
Its neighbours in the OUTLIER dictionary - shortest first.
Could you have found ISOENZYME?
OUTLIER is a daily word game. One grid, the same grid for everybody, and the words nobody else spots are the ones that pay. This word was on Day 107 - and most players walked straight past it.
Play today's OUTLIER