The rare daily word game sweeping the globe. Find what's hidden in plain sight.
APOENZYME
Definition of APOENZYME
noun
An inactive haloenzyme lacking a cofactor.
Wiktionary · CC BY-SA
Where it comes from
From apo- + enzyme.
Etymology via Wiktionary (CC BY-SA).
Word DNA
How it is built
Same root, APOENZYME · 1 relative in the game
OUTLIER scores every word on how unusual it is, and that number is not published. Working it out at the board is the game.
APOENZYME in OUTLIER
Players have found it on 1 board so far.
It first turned up on Day 165, 1 November 2026. Nobody has seen it on a board for 6 days.
First ever to find it
on Day 165, 1 November 2026 - before anyone else in Outlier's history. See the Pioneers
Built from these letters
APOENZYME starts with A and ends with E. Sorted, its letters read AEEMNOPYZ - the shape to hunt for when the grid is scrambled. E appears more than once. It uses Z - among the least common letters in written English.
Could you have found APOENZYME?
OUTLIER is a daily word game. One grid, the same grid for everybody, and the words nobody else spots are the ones that pay. This word was on Day 165 - and most players walked straight past it.
Play today's OUTLIER